ISO certificate Hexamethyldisilazane / HMDS CAS NO.999-97-3

Wuhan Kemiworks Chemical Co., Ltd . works on research and development, production and technical services of  organic silicone chemicals & Organic fluoro chemicals, have been specializing in the development and production of silicone & fluoro chemicals for over 20years. Our silicone chemicals are widely used in textile, leather, paint, automotive, electronic, plastic, rubber, construction materials and other fields.

Our main products series: Organic silicone oils,Organic siloxanes, silane coupling agent, Silicone resin , fluoro-silane  ,etc.

We have experienced scientists and engineers, with scientific test methods and advanced testing equipment, 

relying on strict quality assurance system, providing quality assurance of the required products for our customers.

Specification

Package: 150kg/ iron drum

Production capacity: 200mt/month

Applications

It can be used to introduce trimethylsilyl group into organic molecules containing an active hydrogen atom such as alcohols, carboxylic acids, amines etc. The most common industrial application is in production of semi synthetic beta lactum antibiotics as ampicillin and cephalexin.

The usual procedure is to protect the carboxylic group in the antibiotic with HDMS followed by acylation with the desired acylchloride. Finally, desilylation under mild aqueous conditions gives the desired product.